Phylogenetic reconstruction from non-genomic data

Phylogenetic reconstruction from non-genomic data

MOTIVATION Recent results related to horizontal gene transfer suggest that phylogenetic reconstruction cannot be determined conclusively from sequence data, resulting in a shift from approaches based on polymorphism information in DNA or protein sequence to studies aimed at understanding the evolution of complete biological processes. The increasing amount of available information on metabolic ...

Phylogenetic Reconstruction from Genome Order Data

Image Reconstruction from Incomplete Data

Image Reconstruction from Incomplete Data

Phylogenetic Reconstruction from Gene-Rearrangement Data with Unequal Gene Content

Phylogenetic reconstruction from gene-rearrangement data has seen increased attention over the last five years. Existing methods are limited computationally and by the assumption (highly unrealistic in practice) that all genomes have the same gene content. We have recently shown that we can scale our reconstruction tool, GRAPPA, to instances with up to a thousand genomes with no loss of accurac...